There is a nice blog entry describing the #Cellosaurus on the #Addgene blog: https://blog.addgene.org/cellosaurus-a-cell-line-information-database
In a recent review on insect #celllines (https://www.mdpi.com/2075-4450/14/2/104#B16-insects-14-00104) there is a graphical analysis of the proportion of different insect orders contributing to #Cellosaurus insect cell lines. Not suprisingly lepidoptera and diptera contribute for over 91% of these cell lines
I already saw interesting tidbits in the biography section of an #ORCID but this one is quite special!
A new dog mammary gland carcinoma #cellline CMT-1: https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-023-03573-9 but there is already a CMT-1 cell line from dog and from the same type of cancer which was established in 1986! Another example how reviewers and publishers (here #BMC) fail to do their homework
#BehindCellLines #13: The BRO #cellline (https://www.cellosaurus.org/CVCL_7036) seems to have been established by Arnold Lockshin a US researcher who defected with his wife in 1986 to the USSR. For more on this fascinating story see:
https://en.wikipedia.org/wiki/Arnold_Lockshin https://apnews.com/article/340efaa24201571ec560266341815f5f https://www.texasoutlawwriters.com/the-lockshin-conundrum/
@egonw@scholar.social : Maybe your colleague should contact the lab that published: A Novel MitoTimer Reporter Gene for Mitochondrial Content, Structure, ... https://www.sciencedirect.com/science/article/pii/S0021925820415170 (they have used C2C12 with that construct)
Analysis of 200 glycan datasets for CHO-K1 and CHO-S #celllines: CHOGlycoNET: Comprehensive glycosylation reaction network for CHO cell... https://sciencedirect.com/science/article/pii/S1096717622001586
The most cited journal in the #Cellosaurus is by far Stem Cell Research from Elsevier with 1874 citations. Almost all these papers were published since 2015 when they started publishing short reports describing ESC & iPSCs in their "Lab Resources" section. What is highly disturbing is that the number of errors in these papers is quite high (~50% of the papers have at least 1 major error). My impression is that Elsevier is milking labs for $2210 per paper without doing any real editorial checks.
Kondo's group continues to develop #celllines for rare sarcomas (will be CVCL_C7G0 in next #Cellosaurus release): Establishment and characterization of NCC-DSM1-C1: a novel cell line derived from a patient with desmoid fibromatosis https://pubmed.ncbi.nlm.nih.gov/36629983/
We have just put our latest #Cellosaurus newsletter online at https://www.cellosaurus.org/news_archive/cellosaurus_news_10.pdf
An opportunity to learn about the main developments in the last 15 months (Image: DALL-E: a scientist reading a newsletter in the style of N. Rockwell)
I asked ChatGPT to create a mission statement for #Cellosaurus. What it came up with is so good that I am both awed and scared by the power of such language models! #AI #cellline
Based on the ~26,000 publications currently cited in the #Cellosaurus we wanted to estimate how much of the life science literature is available online (either open access or behing a paywall) versus articles that are only available on paper. As we do not cite enough papers from the 1940s & 1950s, we carried out our estimation for the period 1960-2019
Here are the results: 1960's: 87.2%, 1970 to 1990s: stable at 91.5%, 2000's: 98.9%, 2010's: 100%
A wonderful study carried out on the EndoC-betaH1 #cellline (https://cellosaurus.org/CVCL_L909): "A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk":
Henrietta Lacks' hometown will build statue of her where Robert E. Lee sculpture once stood https://abcn.ws/3G776OF (#HeLa #cellline https://www.cellosaurus.org/CVCL_0030)
In addition to the "Virology" field, two new comment fields were introduced in #Cellosaurus Rel.44: "Senescence" and "Donor information". Example: https://www.cellosaurus.org/CVCL_ZT99 #cellline
A nice discussion on the "best human cell line" in the Quantixed blog: https://quantixed.org/2022/10/01/line-up-recommendations-for-the-best-human-cell-line/
#cellline #biology
Starting with rel.44 information regarding the susceptibility of a #cellline to viral infection, the presence of integrated viruses or any other virology-related information are now stored in a new "Virology" comment. Example: https://www.cellosaurus.org/CVCL_B6Y7 (Image credit: https://viralzone.expasy.org/5216)
Release 44 of #Cellosaurus is ready https://cellosaurus.org It contains information regarding 144568 #celllines and cite 25963 publications. Since last release (Sep 22) 2689 entries were created and 11206 updated.
New introductory video: "Why should you use Cellosaurus, the cell line encyclopedia?" https://www.youtube.com/watch?v=xKA2AleIe0g
Many bench scientists are not aware of the #Cellosaurus & how it can help them use & choose the right #celllines Thus we encourage you to share it as widely as possible