Found a nice "fake" twitter account for Mary Kubicek
https://twitter.com/marykubicekNHS, the lab assistant of George Otto Gey. The account has been created by high school students studying the story of the HeLa #cellline
Information on the anatomical site where a #cellline has been sampled has been completely enhanced and is now linked to the UBERON ontology (http://obofoundry.org/ontology/uberon.html). Cell type information has been also standardized and linked to the CL ontology (http://obofoundry.org/ontology/cl.html). Currently we make use of 803 UBERON and 241 CL terms.
@cthoyt @bioregistry Thank you!
Release 46 of #Cellosaurus is ready https://cellosaurus.org It contains information regarding 146062 #celllines and cite 26479 publications. Highlight of this release: enhancement of info on anatomical origin (tissues/organs) and cell type of cell lines.
The #Cellosaurus paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945021/ has reached over 400 citations. Thank you for citing this paper when using the resource
The 1972 paper describing the snake #cellline OpC-89 https://www.cellosaurus.org/CVCL_T718 is quite interesting as 3 of its 5 authors had "atypical" careers: Ruth L Kirschstein was the 1st woman appointed director of an NIH Institute https://en.wikipedia.org/wiki/Ruth_L._Kirschstein Artrice V Bader was the 1st woman to earn a doctorate in biology at Georgetown https://today.advancement.georgetown.edu/georgetown-magazine/2020/women-wall-honoring-underappreciated-legacy/ and Lester E Harris Jr. was an herpetologist that became a creationist
https://www.amazon.com/Galapagos-Creationist-Visits-Darwins-Islands/dp/0812701259
A very significant milestone for the #Cellosaurus: there are now 10,000 papers that have cited one or more Cellosaurus #cellline Research Resource Identifiers (#RRID)
Nice @Addgene blog entry on HEK293 : https://blog.addgene.org/what-the-hek
Interesting paper: "Cancer researchers’ perceptions of the importance of the sex of cell lines, animals, and human samples for cancer biology research" https://www.cell.com/iscience/fulltext/S2589-0042%2823%2900289-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004223002894%3Fshowall%3Dtrue
Release 45 of #Cellosaurus is ready https://cellosaurus.org It contains information regarding 145368 #celllines and cite 26279 publications. #celllines #bioinformatics #biocuration
Today in the #Cellosaurus we have reached 4000 different sequence variations linked to #ClinVar or #dbSNP There are an additional 2450 variants not linked to these two resources. Globally these variations concern 1100 different human genes.
The #Cellosaurus site (https://www.cellosaurus.org/) underwent a facelift: it is still tuned to be as efficient and effective as possible in providing information but now includes a menu bar and is adapted to smaller screens (phones and tablets).
There is a nice blog entry describing the #Cellosaurus on the #Addgene blog: https://blog.addgene.org/cellosaurus-a-cell-line-information-database
In a recent review on insect #celllines (https://www.mdpi.com/2075-4450/14/2/104#B16-insects-14-00104) there is a graphical analysis of the proportion of different insect orders contributing to #Cellosaurus insect cell lines. Not suprisingly lepidoptera and diptera contribute for over 91% of these cell lines
I already saw interesting tidbits in the biography section of an #ORCID but this one is quite special!
A new dog mammary gland carcinoma #cellline CMT-1: https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-023-03573-9 but there is already a CMT-1 cell line from dog and from the same type of cancer which was established in 1986! Another example how reviewers and publishers (here #BMC) fail to do their homework
#BehindCellLines #13: The BRO #cellline (https://www.cellosaurus.org/CVCL_7036) seems to have been established by Arnold Lockshin a US researcher who defected with his wife in 1986 to the USSR. For more on this fascinating story see:
https://en.wikipedia.org/wiki/Arnold_Lockshin https://apnews.com/article/340efaa24201571ec560266341815f5f https://www.texasoutlawwriters.com/the-lockshin-conundrum/
@egonw@scholar.social : Maybe your colleague should contact the lab that published: A Novel MitoTimer Reporter Gene for Mitochondrial Content, Structure, ... https://www.sciencedirect.com/science/article/pii/S0021925820415170 (they have used C2C12 with that construct)
Analysis of 200 glycan datasets for CHO-K1 and CHO-S #celllines: CHOGlycoNET: Comprehensive glycosylation reaction network for CHO cell... https://sciencedirect.com/science/article/pii/S1096717622001586
The most cited journal in the #Cellosaurus is by far Stem Cell Research from Elsevier with 1874 citations. Almost all these papers were published since 2015 when they started publishing short reports describing ESC & iPSCs in their "Lab Resources" section. What is highly disturbing is that the number of errors in these papers is quite high (~50% of the papers have at least 1 major error). My impression is that Elsevier is milking labs for $2210 per paper without doing any real editorial checks.